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PDGFD Protein (AA 250-370)

PDGFD Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2018314
  • Target See all PDGFD Proteins
    PDGFD (Platelet Derived Growth Factor D (PDGFD))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 250-370
    Origin
    • 7
    • 3
    • 2
    • 1
    Human
    Source
    • 4
    • 3
    • 3
    • 2
    • 1
    CHO Cells
    Characteristics
    ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
    Purity
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product PDGFD Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    PDGFD (Platelet Derived Growth Factor D (PDGFD))
    Abstract
    PDGFD Products
    Synonyms
    IEGF Protein, SCDGF-B Protein, SCDGFB Protein, Scdgfb Protein, rSCDGF-B Protein, PDGFD Protein, 1110003I09Rik Protein, platelet derived growth factor D Protein, platelet-derived growth factor, D polypeptide Protein, PDGFD Protein, Pdgfd Protein
    Background
    PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
    Synonyms: platelet-derived growth factor D, IEGF, SCDGFB
    Molecular Weight
    19-21 kDa, observed by reducing SDS-PAGE.
    UniProt
    Q9GZP0
    Pathways
    RTK Signaling, Platelet-derived growth Factor Receptor Signaling
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