PDGFC Protein (AA 235-345)

Catalog No. ABIN2018318

Recombinant PDGFC protein expressed in HEK-293T Cells.

Quick Overview for PDGFC Protein (AA 235-345) (ABIN2018318)

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293T Cells

Purity: > 95 % as analyzed by SDS-PAGE.

Product Details

Protein Characteristics: AA 235-345

Characteristics: ED50 < 1 ng/mL, measured in a cell proliferation assay using 3T3 cells.

Endotoxin Level: < 0.2 EU/μg, determined by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Storage: -80 °C

Storage Comment: Lyophilized recombinant Human Platelet-derived growth factor (PDGF) -CC remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Platelet-derived growth factor (PDGF) -CC should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Expiry Date: 6 months

Target Details

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Target Type: Viral Protein

Background: Platelet-Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. The PDGF family consists of proteins derived from four genes (PDGF -A, -B, -C, and -D) that form four disulfide-linked homodimers (PDGF-AA, -BB, -CC, and -DD) and one heterodimer (PDGF-AB).
Synonyms: PDGF

Molecular Weight: 15-19 kDa, observed by reducing SDS-PAGE.

NCBI Accession: NP_057289

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling