KIT Ligand Protein (KITLG) (AA 26-189)

Catalog No. ABIN2018377

This Recombinant KIT Ligand protein is expressed in HEK-293T Cells.

Quick Overview for KIT Ligand Protein (KITLG) (AA 26-189) (ABIN2018377)

Target: KIT Ligand (KITLG)

Protein Type: Recombinant

Biological Activity: Active

Origin: Rat

Source: HEK-293T Cells

Purity: > 95 % as analyzed by SDS-PAGE.

Product Details

Protein Characteristics: AA 26-189

Characteristics: ED50 < 50 ng/mL, measured in a proliferation assay using TF-1 Cells.

Endotoxin Level: < 0.2 EU/μg, determined by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Storage: -80 °C

Storage Comment: Lyophilized recombinant Rat Stem Cell Factor (SCF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Rat Stem Cell Factor (SCF) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Expiry Date: 6 months

Target Details

Target: KIT Ligand (KITLG)

Alternative Name: Stem Cell Factor (SCF)

Background: Stem Cell Factor (SCF) is a hematopoietic growth factor that binds to the c-Kit receptor. SCF exerts its activity during the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.
Synonyms: Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor

Molecular Weight: 10-20 kDa, observed by reducing SDS-PAGE.

NCBI Accession: NP_068615

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway