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Dermatopontin Protein (DPT) (AA 19-201) (His-Fc tag)

This Recombinant Dermatopontin protein is expressed in Human Cells.
Catalog No. ABIN2115437
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Quick Overview for Dermatopontin Protein (DPT) (AA 19-201) (His-Fc tag) (ABIN2115437)

Target

See all Dermatopontin (DPT) Proteins
Dermatopontin (DPT)

Protein Type

Recombinant

Origin

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Human

Source

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Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 19-201

    Purification tag / Conjugate

    This Dermatopontin protein is labelled with His-Fc tag.

    Purpose

    Recombinant Human Dermatopontin/DPT/TRAMP (C-Fc-6His)

    Sequence

    QYGDYGYPYQ QYHDYSDDGW VNLNRQGFSY QCPQGQVIVA VRSIFSKKEG SDRQWNYACM PTPQSLGEPT ECWWEEINRA GMEWYQTCSN NGLVAGFQSR YFESVLDREW QFYCCRYSKR CPYSCWLTIE YPGHYGEEMD MISYNYDYYI RGATTTFSAV ERDRQWKFIM CRMTEYDCEF ANVVDDIEGR MDEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SREEMTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH

    Characteristics

    Recombinant Human Dermatopontin is produced by our Mammalian expression system and the target gene encoding Gln19-Val201 is expressed with a Fc, 6His tag at the C-terminus.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C

    Storage Comment

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    3 weeks
  • Target

    Dermatopontin (DPT)

    Alternative Name

    Dermatopontin

    Background

    Alternative Names: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP and DPT,Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.
    Synonyms: Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT,

    Molecular Weight

    49.9 kDa

    UniProt

    Q07507
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