Transferrin Receptor Protein (AA 89-760) (His tag)
Quick Overview for Transferrin Receptor Protein (AA 89-760) (His tag) (ABIN2180829)
Target
See all Transferrin Receptor (TFRC) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 89-760
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Purification tag / Conjugate
- This Transferrin Receptor protein is labelled with His tag.
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Sequence
- AA 89-760
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Characteristics
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76 kDa. The protein migrates as 80-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Biological Activity Comment
- Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized rh CD71 /TFR at 10 μg/mL ( 100 μL/well ) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/mL.
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Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (Fc Tag)
TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His-Avi Tag)TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His-Avi Tag,Biotin)TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transferrin Receptor (p90, CD71) (TFRC) (AA 1-763) protein (His tag)custom-made TFRC Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Transferrin Receptor (p90, CD71) (TFRC) (AA 1-760) protein (His tag)custom-made TFRC Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His tag)TFRC Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) protein (GST tag)TFRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His tag)TFRC Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (GST tag)TFRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His-DYKDDDDK-Strep II Tag)TFRC Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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Alternative Name
- CD71
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Background
- CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
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Molecular Weight
- 77.0 kDa
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NCBI Accession
- NP_003225
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UniProt
- P02786
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Pathways
- Transition Metal Ion Homeostasis
Target
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