Decorin Protein (DCN) (AA 17-359) (His tag)
-
- Target See all Decorin (DCN) Proteins
- Decorin (DCN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-359
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Decorin protein is labelled with His tag.
- Sequence
- AA 17-359
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.8 kDa. The protein migrates as 45 kDa or higher under reducing (R) condition (SDS-PAGE) due to different glycosylation.
- Purity
- >90 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product DCN Protein
-
Decorin (DCN) (AA 1-359) protein (GST tag)
DCN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Decorin (DCN) protein (His tag)DCN Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Decorin (DCN) (AA 36-195) protein (His-IF2DI Tag)DCN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Decorin (DCN) (AA 35-354) protein (His tag)DCN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Decorin (DCN) (AA 31-354) protein (His tag)Crystallography grade DCN Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
-
- Target
- Decorin (DCN)
- Alternative Name
- Decorin (DCN Products)
- Synonyms
- CSCD Protein, DSPG2 Protein, PG40 Protein, PGII Protein, PGS2 Protein, SLRR1B Protein, DC Protein, mDcn Protein, cscd Protein, dspg2 Protein, pg40 Protein, pgii Protein, pgs2 Protein, slrr1b Protein, decorin Protein, decorin L homeolog Protein, DCN Protein, Dcn Protein, dcn.L Protein, dcn Protein
- Background
- Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).
- Molecular Weight
- 38.8 kDa
- NCBI Accession
- NP_001911
- Pathways
- Glycosaminoglycan Metabolic Process
-
