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Decorin Protein (DCN) (AA 17-359) (His tag)

Recombinant Decorin protein expressed in HEK-293 Cells.
Catalog No. ABIN2180962
$350.77
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Quick Overview for Decorin Protein (DCN) (AA 17-359) (His tag) (ABIN2180962)

Target

See all Decorin (DCN) Proteins
Decorin (DCN)

Protein Type

Recombinant

Origin

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Human

Source

  • 8
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HEK-293 Cells

Purity

>90 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 17-359

    Purification tag / Conjugate

    This Decorin protein is labelled with His tag.

    Sequence

    AA 17-359

    Characteristics

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.8 kDa. The protein migrates as 45 kDa or higher under reducing (R) condition (SDS-PAGE) due to different glycosylation.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Handling Advice

    Please avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target

    Decorin (DCN)

    Alternative Name

    Decorin

    Background

    Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).

    Molecular Weight

    38.8 kDa

    NCBI Accession

    NP_001911

    Pathways

    Glycosaminoglycan Metabolic Process
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