Decorin Protein (DCN) (His tag)
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- Target See all Decorin (DCN) Proteins
- Decorin (DCN)
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This Decorin protein is labelled with His tag.
- Purpose
- Recombinant Mouse Decorin/DCN Protein (His Tag)
- Sequence
- Gly17-Lys354
- Characteristics
- Recombinant Mouse Decorin is produced by our Mammalian expression system and the target gene encoding Gly17-Lys354 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product DCN Protein
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Decorin (DCN) (AA 1-359) protein (GST tag)
DCN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Decorin (DCN) (AA 36-195) protein (His-IF2DI Tag)DCN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Decorin (DCN) (AA 35-354) protein (His tag)DCN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Decorin (DCN) (AA 31-354) protein (His tag)Crystallography grade DCN Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Decorin (DCN)
- Alternative Name
- Decorin/DCN (DCN Products)
- Synonyms
- CSCD Protein, DSPG2 Protein, PG40 Protein, PGII Protein, PGS2 Protein, SLRR1B Protein, DC Protein, mDcn Protein, cscd Protein, dspg2 Protein, pg40 Protein, pgii Protein, pgs2 Protein, slrr1b Protein, decorin Protein, decorin L homeolog Protein, DCN Protein, Dcn Protein, dcn.L Protein, dcn Protein
- Background
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Background: Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a guardian from the matrix. Mature human Decorin contains 12 tandem LRR and shares 80 % and 78 % aa sequence identity with mouse and rat Decorin, respectively. Decorin embraces numerous functions including: regulation of collagen fibrillogenesis, hepatic carcinogenesis, fetal membrane and calcium homeostasis, keratinocyte function, and suppression of angiogenesis. Most recently, soluble decorin has been shown to induce autophagy in endothelial cells and mitophagy in breast carcinoma cells.
Synonym: Decorin, Bone proteoglycan II, PG-S2, PG40, Dcn
- Molecular Weight
- 39.0 kDa
- UniProt
- P28654
- Pathways
- Glycosaminoglycan Metabolic Process
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