IL-24 Protein
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- Target See all IL-24 (IL24) Proteins
- IL-24 (IL24) (Interleukin 24 (IL24))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- CHO Cells
- Sequence
- QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H
- Purity
- < 95 % by SDS-PAGE gel and HPLC analyses.
- Top Product
- Discover our top product IL24 Protein
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Interleukin 24 (IL24) (AA 51-206) (Active) protein (His tag)
IL24 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
Interleukin 24 (IL24) (AA 1-207) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-206) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 58-167) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 52-206) protein (His tag)Crystallography grade IL24 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 24 (IL24) (AA 27-181) protein (His tag)Crystallography grade IL24 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Handling Advice
- As with any protein, exposing IL-24 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -20 °C
- Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-24 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Expiry Date
- 24 months
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- Target
- IL-24 (IL24) (Interleukin 24 (IL24))
- Alternative Name
- IL-24 (IL24 Products)
- Synonyms
- C49A Protein, FISP Protein, IL10B Protein, MDA7 Protein, MOB5 Protein, ST16 Protein, Mda7 Protein, St16 Protein, Mda-7 Protein, IL24 Protein, interleukin 24 Protein, IL24 Protein, Il24 Protein
- Background
- IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
- Gene ID
- 11009
- NCBI Accession
- NP_001172085
- OMIM
- 297632401
- UniProt
- Q13007
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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