TNFSF14 Protein
Quick Overview for TNFSF14 Protein (ABIN2468760)
Target
See all TNFSF14 ProteinsProtein Type
Origin
Source
Purity
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Sequence
- MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
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Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 89-240), (Trimer) (Active) protein (His-DYKDDDDK Tag)
TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) (Active) protein (His tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) (Active) protein (hFc Tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 99-330) protein (Fc Tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239) protein (His tag)custom-made TNFSF14 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-240) protein (His tag)custom-made TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 89-240) protein (His-DYKDDDDK-Strep II Tag)TNFSF14 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) (Active) protein (His tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-204) protein (GST tag)TNFSF14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-177) protein (GST tag)TNFSF14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Handling Advice
- As with any protein, exposing LIGHT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Storage
- -20 °C
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Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Expiry Date
- 24 months
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- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
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Background
- LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.
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Gene ID
- 50930
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NCBI Accession
- NP_062291
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OMIM
- 9507195
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UniProt
- Q9QYH9
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Pathways
- Cancer Immune Checkpoints
Target
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