MTCH2 Protein (AA 29-174) (His tag)
This Recombinant MTCH2 protein is produced in Escherichia coli (E. coli).
1 image
Catalog No. ABIN2468870
$334.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 µg
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United States
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Quick Overview for MTCH2 Protein (AA 29-174) (His tag) (ABIN2468870)
Target
See all MTCH2 Proteins
MTCH2
(Mitochondrial Carrier 2 (MTCH2))
Protein Type
Recombinant
Origin
Mouse
Source
Escherichia coli (E. coli)
Application
Western Blotting (WB), Mass Spectrometry (MS), Neutralization (Neut), ELISA
Purity
~95 %
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Protein Characteristics
- AA 29-174
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Purification tag / Conjugate
- This MTCH2 protein is labelled with His tag.
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Mitochondrial Carrier 2 (MTCH2) (AA 1-303) protein (GST tag)
MTCH2 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 1X PBS containing 0.1 % SDS
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Handling Advice
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Storage
- -80 °C
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Storage Comment
- Store in working aliquots at -70 °C.
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- MTCH2 (Mitochondrial Carrier 2 (MTCH2))
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Alternative Name
- MTCH2
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Background
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals (4-6), suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. The doublet observed in the SDS-PAGE is likely due to incomplete removal of the signal sequence.
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Molecular Weight
- 19 kDa (Calculated)
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Gene ID
- 56428
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NCBI Accession
- NP_055157
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OMIM
- 5815347
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UniProt
- Q791V5
Target
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