MSTN Protein (Propeptide)
Quick Overview for MSTN Protein (Propeptide) (ABIN2468877)
Target
See all MSTN ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- Propeptide
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Sequence
- MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
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Characteristics
- Biological activity was determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC - 11 cells. The expected ED50is 0.01 - 0.04 μg/mL in the presence of 50 ng/mL Myostatin.
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Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Myostatin (MSTN) (Active) protein
MSTN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Myostatin (MSTN) (AA 24-375) protein (Fc Tag)MSTN Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Myostatin (MSTN) (AA 267-375) protein (His-IF2DI Tag)MSTN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Myostatin (MSTN) (AA 1-375) protein (GST tag)MSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Myostatin (MSTN) proteinMSTN Origin: Human Host: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Handling Advice
- As with any protein, exposing Myostatin Propeptide recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Storage
- -20 °C
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Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Myostatin Propeptide is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Expiry Date
- 24 months
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- MSTN (Myostatin (MSTN))
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Alternative Name
- Myostatin
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Background
- Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200 % ) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.
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Gene ID
- 2660
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NCBI Accession
- NP_005250
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OMIM
- 4885259
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UniProt
- O14793
Target
-
