Placenta Growth Factor 1 (PIGF-1) (Active) Protein

Catalog No. ABIN2468975

This Recombinant Placenta Growth Factor 1 protein is produced in Escherichia coli (E. coli).

Quick Overview for Placenta Growth Factor 1 (PIGF-1) (Active) Protein (ABIN2468975)

Target: Placenta Growth Factor 1 (PIGF-1)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: < 95 % by SDS-PAGE gel and HPLC analyses.

Product Details

Sequence: MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR

Characteristics: Biological activity was determined by its ability to chemoattract human monocytes of using a concentration range of 1.0 - 10.0 ng/mL.

Endotoxin Level: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Handling Advice: As with any protein, exposing PlGF-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Storage: -20 °C

Storage Comment: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted PlGF-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Expiry Date: 24 months

Target Details

Target: Placenta Growth Factor 1 (PIGF-1)

Background: PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 131 amino acid polypeptide chains.

Gene ID: 5228

NCBI Accession: NP_001193941

OMIM: 333033785

UniProt: P49763