Placenta Growth Factor 3 (PIGF-3) (Active) Protein
Recombinant Placenta Growth Factor 3 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2468980
$295.63
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Quick Overview for Placenta Growth Factor 3 (PIGF-3) (Active) Protein (ABIN2468980)
Target
Placenta Growth Factor 3 (PIGF-3)
Protein Type
Recombinant
Biological Activity
Active
Origin
Human
Source
Escherichia coli (E. coli)
Purity
< 95 % by SDS-PAGE gel and HPLC analyses.
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Sequence
- LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRHSPGRQS PDMPGDFRAD APSFLPPRRS LPMLFRMEWG CALTGSQSAV WPSSPVPEEI PRMHPGRNGK KQQRKPLREK MKPERCGDAV PRR
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Characteristics
- Biological activity was determined by its ability to chemoattract human monocytes using a concentration range of 5.0 - 50.0 ng/mL.
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Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Handling Advice
- As with any protein, exposing PlGF-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Storage
- -20 °C
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Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted PlGF-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Expiry Date
- 24 months
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- Placenta Growth Factor 3 (PIGF-3)
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Background
- PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PlGF-3 lacks heparin binding affinity. Recombinant human PlGF-3 is a 45.7 kDa disulfide-linked homodimeric protein of two 203 amino acid polypeptide chains.
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Gene ID
- 5228
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NCBI Accession
- NP_001193941
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OMIM
- 333033785
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UniProt
- P49763
Target
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