Viral MIP-2 (Active) Protein
Origin: Virus, Human Herpesvirus 8 (HHV-8)
Host: Escherichia coli (E. coli)
Recombinant
< 98 % by SDS-PAGE gel and HPLC analyses.
Active
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- Target
- Viral MIP-2
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Virus, Human Herpesvirus 8 (HHV-8)
- Source
- Escherichia coli (E. coli)
- Sequence
- LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA
- Characteristics
- Determined by the inhibitory effect on monocyte migration response to human MIP - 1 alpha using a concentration range of 1.0 μg - 10.0 μg/mL of viral MIP - 2 will inhibit 25 ng/mL of human MIP - 1 alpha.
- Purity
- < 98 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Handling Advice
- As with any protein, exposing Viral MIP-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -20 °C
- Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Viral MIP-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Expiry Date
- 24 months
-
- Target
- Viral MIP-2
- Target Type
- Viral Protein
- Background
- VMIP-2 is a chemokine analog encoded by human herpes virus, and has been shown to have antagonist activity towards several chemokine receptors. Recombinant vMIP-2 is a 7.9 kDa protein consisting of 70 amino acids including the four highly conserved cysteine residues present in CC chemokines.
- Gene ID
- 4961514
- NCBI Accession
- YP_001129362
- OMIM
- 139472814
- UniProt
- Q98157
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