TYRO3 Protein (Fc Tag)
Quick Overview for TYRO3 Protein (Fc Tag) (ABIN2567003)
Target
See all TYRO3 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TYRO3 protein is labelled with Fc Tag.
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Characteristics
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Measured by its binding ability in a functional ELISA. Immobilized rh TYRO3 / DTK Fc Chimera at 2 μg/mL (100 μL/well) can bind rhGas6 with a linear range of 10 - 100 ng/mL.
Fusion tag: C-Fc Tag
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Application Notes
- This recombinant protein can be used for WB, ELISA. For research use only.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM tris, 100 mM glycine, pH 7.5
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Storage
- -80 °C,-20 °C
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Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
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Alternative Name
- TYRO3
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Background
- Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.
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Molecular Weight
- 68.2 kDa
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Gene ID
- 7301
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UniProt
- Q06418
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Pathways
- RTK Signaling
Target
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