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TYRO3 Protein (Fc Tag)

Recombinant TYRO3 protein expressed in HEK-293 Cells.
Catalog No. ABIN2567003
$708.13
Plus shipping costs $50.00
200 μg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for TYRO3 Protein (Fc Tag) (ABIN2567003)

Target

See all TYRO3 Proteins
TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 13
  • 7
  • 2
  • 1
  • 1
  • 1
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  • 1
Human

Source

  • 9
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Application

ELISA, Western Blotting (WB)

Purity

>95 % as determined by SDS-PAGE.
  • Purification tag / Conjugate

    This TYRO3 protein is labelled with Fc Tag.

    Characteristics

    Measured by its binding ability in a functional ELISA. Immobilized rh TYRO3 / DTK Fc Chimera at 2 μg/mL (100 μL/well) can bind rhGas6 with a linear range of 10 - 100 ng/mL.

    Fusion tag: C-Fc Tag

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  • Application Notes

    This recombinant protein can be used for WB, ELISA. For research use only.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    50 mM tris, 100 mM glycine, pH 7.5

    Storage

    -80 °C,-20 °C

    Storage Comment

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target

    TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

    Alternative Name

    TYRO3

    Background

    Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.

    Molecular Weight

    68.2 kDa

    Gene ID

    7301

    UniProt

    Q06418

    Pathways

    RTK Signaling
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