CEA Protein

Catalog No. ABIN2648102

This Native CEA protein is expressed in Human and has been mentioned in 1 publication.

Quick Overview for CEA Protein (ABIN2648102)

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Protein Type: Native

Origin: Human

Source: Human

Purity: > 98 % pure

Product Details

Characteristics: Purified native Human CEA protein
Protein Source: Purified human colon carcinoma

Purification: Immunoaffinity column

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a liquid in 10 mM PBS, pH 7.5, with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

References

Lima, Jenkins, Guerrero, Triozzi, Shaw, Strong: "A DNA vaccine encoding genetic fusions of carcinoembryonic antigen (CEA) and granulocyte/macrophage colony-stimulating factor (GM-CSF)." in: Vaccine, Vol. 23, Issue 10, pp. 1273-83, (2005) (PubMed).

Target Details

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Alternative Name: CEA

Background: Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
Description: Purified human colon carcinoma.
Alternative Names: Carcinoembryonic Antigen protein