DAAM1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712410

Product Details

Target: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DAAM1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human DAAM1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Alternative Name: Daam1 (DAAM1 Products)

Synonyms: 1700066F09Rik Protein, 2310028E21Rik Protein, AI503486 Protein, E130308H01 Protein, mKIAA0666 Protein, daam-1 Protein, xdaam1 Protein, daam1 Protein, DAAM1 Protein, DKFZp468D0524 Protein, daam1l Protein, fc83b10 Protein, si:ch211-87i20.1 Protein, wu:fc83b10 Protein, dishevelled associated activator of morphogenesis 1 Protein, dishevelled associated activator of morphogenesis 1 S homeolog Protein, dishevelled associated activator of morphogenesis 1a Protein, dishevelled associated activator of morphogenesis 1b Protein, DAAM1 Protein, Daam1 Protein, daam1.S Protein, daam1a Protein, daam1 Protein, daam1b Protein

Background: Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Molecular Weight: 123.3 kDa

NCBI Accession: NP_055807

Pathways: WNT Signaling