COPS8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712497

Recombinant COPS8 protein expressed in HEK-293 Cells.

Quick Overview for COPS8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2712497)

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This COPS8 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human COPS8 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Alternative Name: Cops8

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molecular Weight: 17.7 kDa

NCBI Accession: NP_937832

Pathways: Cell Division Cycle