CRLF2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for CRLF2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2712563)
Target
See all CRLF2 ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Protein Characteristics
- Transcript Variant 1
-
Purification tag / Conjugate
- This CRLF2 protein is labelled with Myc-DYKDDDDK Tag.
-
Characteristics
-
- Recombinant human CRLF2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
-
The tag is located at the C-terminal.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 50 μg/mL
-
Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
Storage
- -80 °C
-
Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
-
Alternative Name
- Crlf2
-
Background
- This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
-
Molecular Weight
- 41.8 kDa
-
NCBI Accession
- NP_071431
Target
-