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CRLF2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Recombinant CRLF2 protein expressed in HEK-293 Cells.
Catalog No. ABIN2712563
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
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Quick Overview for CRLF2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2712563)

Target

See all CRLF2 Proteins
CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Protein Type

Recombinant

Origin

  • 12
  • 6
  • 1
  • 1
Human

Source

  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This CRLF2 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CRLF2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

    Alternative Name

    Crlf2

    Background

    This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

    Molecular Weight

    41.8 kDa

    NCBI Accession

    NP_071431
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