Quick Overview for CYP2C9 Protein (Myc-DYKDDDDK Tag) (ABIN2712767)
Target
See all CYP2C9 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CYP2C9 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CYP2C9 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9) (AA 1-490) protein (His tag)
custom-made CYP2C9 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9) (AA 1-162) protein (GST tag)CYP2C9 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
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Alternative Name
- Cyp2c9
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Background
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
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Molecular Weight
- 55.4 kDa
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NCBI Accession
- NP_000762
Target
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