Claudin 1 Protein (CLDN1) (Myc-DYKDDDDK Tag)
Quick Overview for Claudin 1 Protein (CLDN1) (Myc-DYKDDDDK Tag) (ABIN2712852)
Target
See all Claudin 1 (CLDN1) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Claudin 1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Claudin-1 / CLDN1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Claudin 1 (CLDN1) (AA 1-211) protein (His tag)
custom-made CLDN1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 1 (CLDN1) (AA 1-211) protein (His tag)custom-made CLDN1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 1 (CLDN1) (AA 1-211) protein (GST tag)CLDN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Claudin 1 (CLDN1)
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Alternative Name
- Claudin-1,cldn1
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Background
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
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Molecular Weight
- 22.6 kDa
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NCBI Accession
- NP_066924
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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