Claudin 1 Protein (CLDN1) (AA 29-115) (His tag)
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- Target See all Claudin 1 (CLDN1) Proteins
- Claudin 1 (CLDN1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-115
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Claudin 1 protein is labelled with His tag.
- Sequence
- Gln29-Lys115
- Characteristics
- A DNA sequence encoding theHuman CLDN1 protein (O95832) (Gln29-Lys115) was expressed with a N-His.
- Purity
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CLDN1 Protein
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Claudin 1 (CLDN1) (AA 1-211) protein (GST tag)
CLDN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Claudin 1 (CLDN1) (AA 1-211) protein (Strep Tag)Crystallography grade CLDN1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Claudin 1 (CLDN1) (AA 1-211) protein (Strep Tag)Crystallography grade CLDN1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Claudin 1 (CLDN1) protein (Myc-DYKDDDDK Tag)CLDN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Claudin 1 (CLDN1)
- Alternative Name
- CLDN1 (CLDN1 Products)
- Synonyms
- CLD1 Protein, ILVASC Protein, SEMP1 Protein, AI596271 Protein, cldn19 Protein, claudin-1 Protein, cld1 Protein, ilvasc Protein, semp1 Protein, CLDN1 Protein, claudin 1 Protein, claudin 1 S homeolog Protein, CLDN1 Protein, Cldn1 Protein, cldn1 Protein, cldn1.S Protein
- Background
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Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.
Synonym: Senescence-associated epithelial membrane protein
- Molecular Weight
- 9.6 kDa
- UniProt
- O95832
- Pathways
- Cell-Cell Junction Organization, Hepatitis C
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