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CNOT7 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

This Recombinant CNOT7 protein is produced in HEK-293 Cells.
Catalog No. ABIN2712912
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for CNOT7 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2712912)

Target

See all CNOT7 Proteins
CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Protein Type

Recombinant

Origin

  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This CNOT7 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CNOT7 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
    Origin
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $12,595.45
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

    Alternative Name

    Cnot7

    Background

    The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

    Molecular Weight

    32.6 kDa

    NCBI Accession

    NP_037486

    Pathways

    Ribonucleoprotein Complex Subunit Organization
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