CDH23 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for CDH23 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2713021)
Target
See all CDH23 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This CDH23 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Cadherin-23 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CDH23 (Cadherin 23 (CDH23))
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Alternative Name
- Cadherin-23
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Background
- This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.
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Molecular Weight
- 58.4 kDa
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NCBI Accession
- NP_443068
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Pathways
- Sensory Perception of Sound
Target
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