RCAN1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for RCAN1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713037)
Target
See all RCAN1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This RCAN1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Calcipressin-1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Regulator of Calcineurin 1 (RCAN1) (AA 1-117) protein
RCAN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Regulator of Calcineurin 1 (RCAN1) (AA 1-117), (Isoform B) proteinRCAN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Regulator of Calcineurin 1 (RCAN1) (AA 1-197) protein (GST tag)RCAN1 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Alternative Name
- Calcipressin-1
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Background
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 27.9 kDa
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NCBI Accession
- NP_004405
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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