CASC3 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713190

Recombinant CASC3 protein expressed in HEK-293 Cells.

Quick Overview for CASC3 Protein (Myc-DYKDDDDK Tag) (ABIN2713190)

Target: CASC3 (Cancer Susceptibility Candidate 3 (CASC3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This CASC3 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human CASC3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CASC3 (Cancer Susceptibility Candidate 3 (CASC3))

Alternative Name: Casc3

Background: The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.

Molecular Weight: 76.1 kDa

NCBI Accession: NP_031385