Integrin beta 4 Protein (ITGB4) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for Integrin beta 4 Protein (ITGB4) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713356)
Target
See all Integrin beta 4 (ITGB4) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This Integrin beta 4 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD104 / Integrin beta-4 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Integrin beta 4 (ITGB4) (AA 28-137) protein (GST tag)
ITGB4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Integrin beta 4 (ITGB4) (AA 29-256) protein (His-IF2DI Tag)ITGB4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Integrin beta 4 (ITGB4) (AA 28-710) protein (His tag)ITGB4 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Integrin beta 4 (ITGB4)
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Alternative Name
- Cd104,integrin beta-4
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Background
- Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Molecular Weight
- 199.4 kDa
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NCBI Accession
- NP_000204
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Pathways
- Integrin Complex
Target
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