PVRL2 Protein (Myc-DYKDDDDK Tag)
Quick Overview for PVRL2 Protein (Myc-DYKDDDDK Tag) (ABIN2713372)
Target
See all PVRL2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PVRL2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD112 / Nectin 2 (transcript variant delta) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
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Alternative Name
- Cd112,nectin 2
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Background
- This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Molecular Weight
- 54.4 kDa
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NCBI Accession
- NP_001036189
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
Target
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