CD1e Protein (CD1e) (Transcript Variant 8) (Myc-DYKDDDDK Tag)
Quick Overview for CD1e Protein (CD1e) (Transcript Variant 8) (Myc-DYKDDDDK Tag) (ABIN2713482)
Target
See all CD1e ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 8
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Purification tag / Conjugate
- This CD1e protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD1e (transcript variant 8) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CD1e
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Alternative Name
- CD1e Molecule (Cd1e)
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Background
- This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found however, their biological validity has not been determined.
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Molecular Weight
- 32.7
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NCBI Accession
- NP_001172044
Target
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