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CD2AP Protein (Myc-DYKDDDDK Tag)

Cd2ap Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713486
  • Target See all CD2AP (Cd2ap) Proteins
    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    • 1
    Human
    Source
    • 4
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This CD2AP protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CD2-associated protein protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product Cd2ap Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
    Alternative Name
    CD2-Associated Protein (Cd2ap Products)
    Synonyms
    cd2apl Protein, fj51c01 Protein, im:7153970 Protein, si:ch211-207n9.1 Protein, wu:fj51c01 Protein, zgc:103705 Protein, DKFZp469E061 Protein, CMS Protein, AL024079 Protein, C78928 Protein, METS-1 Protein, Mets1 Protein, CD2-associated protein L homeolog Protein, CD2 associated protein Protein, CD2-associated protein Protein, cd2ap.L Protein, CD2AP Protein, cd2ap Protein, Cd2ap Protein
    Background
    This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
    Molecular Weight
    71.3 kDa
    NCBI Accession
    NP_036252
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