ICAM4 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713529

Recombinant ICAM4 protein expressed in HEK-293 Cells.

Quick Overview for ICAM4 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2713529)

Target: ICAM4 (Intercellular Adhesion Molecule 4 (ICAM4))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 3

Purification tag / Conjugate: This ICAM4 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human CD242 / ICAM4 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ICAM4 (Intercellular Adhesion Molecule 4 (ICAM4))

Alternative Name: Cd242,icam4

Background: This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100 Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 27.4 kDa

NCBI Accession: NP_001034221