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CD276 Protein (CD276) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

This Recombinant CD276 protein is expressed in HEK-293 Cells.
Catalog No. ABIN2713597
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for CD276 Protein (CD276) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2713597)

Target

See all CD276 Proteins
CD276

Protein Type

Recombinant

Origin

  • 44
  • 14
  • 3
  • 2
Human

Source

  • 44
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 2

    Purification tag / Conjugate

    This CD276 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CD276 / B7H3 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    CD276

    Alternative Name

    Cd276,b7h3

    Background

    The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    33.6 kDa

    NCBI Accession

    NP_079516

    Pathways

    Cancer Immune Checkpoints
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