JAG1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713680

This Recombinant JAG1 protein is produced in HEK-293 Cells.

Quick Overview for JAG1 Protein (Myc-DYKDDDDK Tag) (ABIN2713680)

Target: JAG1 (Jagged 1 (JAG1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This JAG1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human CD339 / JAG1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: Cd339,jag1

Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Molecular Weight: 133.6 kDa

NCBI Accession: NP_000205

Pathways: Notch Signaling, Stem Cell Maintenance