ITGA3 Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713729

This Recombinant ITGA3 protein is expressed in HEK-293 Cells.

Quick Overview for ITGA3 Protein (Transcript Variant B) (Myc-DYKDDDDK Tag) (ABIN2713729)

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant B

Purification tag / Conjugate: This ITGA3 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human CD49c / ITGA3 (transcript variant b) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Alternative Name: Cd49c,itga3

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis.

Molecular Weight: 115.6 kDa

NCBI Accession: NP_005492

Pathways: CXCR4-mediated Signaling Events, Integrin Complex