Quick Overview for ITGA4 Protein (Myc-DYKDDDDK Tag) (ABIN2713730)
Target
See all ITGA4 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This ITGA4 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD49d / ITGA4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Integrin alpha 4 (ITGA4) (AA 98-207) protein (GST tag)
ITGA4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Integrin alpha 4 (ITGA4) (AA 790-1032) protein (His-IF2DI Tag)ITGA4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Integrin alpha 4 (ITGA4) (AA 131-275) protein (His tag)ITGA4 Origin: Human Host: Escherichia coli (E. coli) Recombinant ~95 % WB, ELISA, MS, Neut
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ITGA4 (Integrin alpha 4 (ITGA4))
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Alternative Name
- Cd49d,itga4
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Background
- The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 111.2 kDa
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NCBI Accession
- NP_000876
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Pathways
- Integrin Complex
Target
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