CDC42 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all CDC42 Proteins
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CDC42 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CDC42 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CDC42 Protein
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Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-188) protein (T7 tag)
CDC42 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) protein (GST-pstS1)CDC42 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) protein (GST tag)CDC42 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CDC42 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)CDC42 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- Alternative Name
- Cdc42 (CDC42 Products)
- Background
- The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
- Molecular Weight
- 21.1 kDa
- NCBI Accession
- NP_001782
- Pathways
- MAPK Signaling, Microtubule Dynamics, RTK Signaling, WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
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