Quick Overview for CDK5 Protein (Myc-DYKDDDDK Tag) (ABIN2713865)
Target
See all CDK5 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CDK5 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CDK5 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) protein (His tag)
custom-made CDK5 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) protein (His tag)custom-made CDK5 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) protein (GST tag)CDK5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) protein (His tag)CDK5 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
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Alternative Name
- Cdk5
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Background
- This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 33.1 kDa
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NCBI Accession
- NP_004926
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Pathways
- Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
Target
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