Quick Overview for CDK6 Protein (Myc-DYKDDDDK Tag) (ABIN2713868)
Target
See all CDK6 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CDK6 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CDK6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Cyclin-Dependent Kinase 6 (CDK6) (AA 1-326) protein (His tag)
custom-made CDK6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin-Dependent Kinase 6 (CDK6) (AA 1-326) protein (His tag)custom-made CDK6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin-Dependent Kinase 6 (CDK6) (AA 1-326) protein (GST tag)CDK6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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Alternative Name
- Cdk6
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Background
- The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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Molecular Weight
- 36.8 kDa
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NCBI Accession
- NP_001250
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Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases
Target
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