CHMP2B Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713982

Recombinant CHMP2B protein expressed in HEK-293 Cells.

Quick Overview for CHMP2B Protein (Myc-DYKDDDDK Tag) (ABIN2713982)

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This CHMP2B protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human CHMP2B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Alternative Name: Chmp2b

Background: This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.

Molecular Weight: 23.7 kDa

NCBI Accession: NP_054762