Quick Overview for Actl7b Protein (Myc-DYKDDDDK Tag) (ABIN2714372)
Target
See all Actl7b ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Actl7b protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ACTL7B protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Actin-Like 7b (Actl7b) (AA 1-415) protein (His tag)
custom-made Actl7b Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Actin-Like 7b (Actl7b) (AA 1-418) protein (His tag)custom-made Actl7b Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Actin-Like 7b (Actl7b) (AA 1-415) protein (GST tag)Actl7b Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Actl7b (Actin-Like 7b (Actl7b))
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Alternative Name
- Actl7b
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Background
- The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
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Molecular Weight
- 45.1 kDa
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NCBI Accession
- NP_006677
Target
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