Adenylosuccinate Lyase Protein (ADSL) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for Adenylosuccinate Lyase Protein (ADSL) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2714408)
Target
See all Adenylosuccinate Lyase (ADSL) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This Adenylosuccinate Lyase protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Adenylosuccinate lyase / ASL (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Adenylosuccinate Lyase (ADSL) (AA 1-484) protein (GST tag)
ADSL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Adenylosuccinate Lyase (ADSL) (AA 1-484) protein (His-IF2DI Tag)ADSL Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Adenylosuccinate Lyase (ADSL) (AA 1-484) protein (His tag)ADSL Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Adenylosuccinate Lyase (ADSL)
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Alternative Name
- Adenylosuccinate Lyase (Asl)
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Background
- The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.
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Molecular Weight
- 54.7 kDa
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NCBI Accession
- NP_000017
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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