Catalog No. ABIN2714459
$1,112.40
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20 μg
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United States
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Quick Overview for ASIP Protein (Myc-DYKDDDDK Tag) (ABIN2714459)
Target
See all ASIP Proteins
ASIP
(Agouti Signaling Protein (ASIP))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Purification tag / Conjugate
- This ASIP protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Agouti-signaling protein (ASP) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Agouti Signaling Protein (ASIP) (AA 33-132) protein (GST tag)
ASIP Origin: Human Host: Wheat germ Recombinant ELISA, AA, AP, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ASIP (Agouti Signaling Protein (ASIP))
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Alternative Name
- Agouti-Signaling Protein (Asp)
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Background
- In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
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Molecular Weight
- 12 kDa
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NCBI Accession
- NP_001663
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Pathways
- Cell-Cell Junction Organization, Feeding Behaviour
Target
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