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P5CS Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Recombinant P5CS protein expressed in HEK-293 Cells.
Catalog No. ABIN2714537

Quick Overview for P5CS Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2714537)

Target

See all P5CS (ALDH18A1) Proteins
P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Protein Type

Recombinant

Origin

  • 3
  • 2
Human

Source

  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This P5CS protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human ALDH18A1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
    Origin
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $12,595.45
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    Conjugate Strep Tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

    Alternative Name

    Aldh18a1

    Background

    This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

    Molecular Weight

    87.1 kDa

    NCBI Accession

    NP_002851
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