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ALOX5 Protein (Myc-DYKDDDDK Tag)

Recombinant ALOX5 protein expressed in HEK-293 Cells.
Catalog No. ABIN2714585

Quick Overview for ALOX5 Protein (Myc-DYKDDDDK Tag) (ABIN2714585)

Target

See all ALOX5 Proteins
ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Protein Type

Recombinant

Origin

  • 7
  • 4
  • 3
Human

Source

  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This ALOX5 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human ALOX5 / LOG5 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $12,595.45
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

    Alternative Name

    Alox5,log5

    Background

    This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    77.8 kDa

    NCBI Accession

    NP_000689
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