ANAPC2 Protein (Myc-DYKDDDDK Tag)
Quick Overview for ANAPC2 Protein (Myc-DYKDDDDK Tag) (ABIN2714781)
Target
See all ANAPC2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This ANAPC2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human APC2 / ANAPC2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))
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Alternative Name
- Apc2,anapc2
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Background
- A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.
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Molecular Weight
- 93.6 kDa
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NCBI Accession
- NP_037498
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Pathways
- Regulation of Cell Size
Target
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