ARNT2 Protein (Myc-DYKDDDDK Tag)
Quick Overview for ARNT2 Protein (Myc-DYKDDDDK Tag) (ABIN2714934)
Target
See all ARNT2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This ARNT2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ARNT2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))
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Alternative Name
- Arnt2
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Background
- This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
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Molecular Weight
- 78.5 kDa
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NCBI Accession
- NP_055677
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Pathways
- Warburg Effect
Target
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