Asialoglycoprotein Receptor 1 Protein (ASGR1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714979

This Recombinant Asialoglycoprotein Receptor 1 protein is produced in HEK-293 Cells.

Quick Overview for Asialoglycoprotein Receptor 1 Protein (ASGR1) (Myc-DYKDDDDK Tag) (ABIN2714979)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Asialoglycoprotein Receptor 1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human ASGR1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: Asgr1

Background: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. [UniProtKB/Swiss-Prot Function]

Molecular Weight: 33 kDa

NCBI Accession: NP_001662

Pathways: Thyroid Hormone Synthesis