Asialoglycoprotein Receptor 2 Protein (ASGR2) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for Asialoglycoprotein Receptor 2 Protein (ASGR2) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2714982)
Target
See all Asialoglycoprotein Receptor 2 (ASGR2) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This Asialoglycoprotein Receptor 2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ASGR2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Asialoglycoprotein Receptor 2 (ASGR2)
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Alternative Name
- Asgr2
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Background
- This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Molecular Weight
- 35 kDa
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NCBI Accession
- NP_001172
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Pathways
- Thyroid Hormone Synthesis
Target
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