ASPSCR1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for ASPSCR1 Protein (Myc-DYKDDDDK Tag) (ABIN2715005)
Target
See all ASPSCR1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This ASPSCR1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ASPSCR1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
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Alternative Name
- Aspscr1
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Background
- The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X17)(p11q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.
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Molecular Weight
- 60 kDa
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NCBI Accession
- NP_076988
Target
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