ATP1B2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715040

This Recombinant ATP1B2 protein is expressed in HEK-293 Cells.

Quick Overview for ATP1B2 Protein (Myc-DYKDDDDK Tag) (ABIN2715040)

Target: ATP1B2 (ATPase, Na+/K+ Transporting, beta 2 Polypeptide (ATP1B2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This ATP1B2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human ATP1B2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ATP1B2 (ATPase, Na+/K+ Transporting, beta 2 Polypeptide (ATP1B2))

Alternative Name: Atp1b2

Background: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 33.2 kDa

NCBI Accession: NP_001669

Pathways: Thyroid Hormone Synthesis